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Registro Completo |
Biblioteca(s): |
Embrapa Meio Ambiente. |
Data corrente: |
01/11/2018 |
Data da última atualização: |
01/11/2018 |
Tipo da produção científica: |
Artigo em Periódico Indexado |
Autoria: |
BARRETO, F. M.; SILVA, M. R. da; BRAGA, P. A. C.; BRAGOTTO, A. P. A.; HISANO, H.; REYES, F. G. R. |
Afiliação: |
FABIOLA MALAGA BARRETO, FEA-UNICAMP; MARIANA R DA SILVA, FEA-UNICAMP; PATRICIA APARECIDA DE CAMPOS BRAGA, FEA-UNICAMP; ADRIANA PAVESI ARISSETO BRAGOTTO, FEA-UNICAMP; HAMILTON HISANO, CNPMA; FELIX GUILLERMO REYES REYES, FEA-UNICAMP. |
Título: |
Evaluation of the leaching of florfenicol from coated medicated fish feed into water. |
Ano de publicação: |
2018 |
Fonte/Imprenta: |
Environmental Pollution, v. 242, Part B, p. 1245-1252, 2018. |
ISSN: |
0269-7491 |
DOI: |
https://doi.org/10.1016/j.envpol.2018.08.017 |
Idioma: |
Inglês |
Conteúdo: |
Florfenicol is one of the most-used antimicrobial agents in global fish farming. Nevertheless, in most countries, its use is not conducted in accordance with good practices. The aim of this work was to evaluate the leaching of florfenicol from coated fish feed into the water. Analytical methods were developed and validated for the quantitation of florfenicol in medicated feed and water by UHPLC-MS/MS. Florfenicol residues in the water were quantified after 5- and 15-min exposures of the medicated feed in the water at 22 and 28°C and at pH 4.5 and 8.0. The influence of pellet size and three coating agents (vegetable oil, carboxymethylcellulose, and low-methoxylated pectin) on the leaching of the drug was also assessed. Pellet size, coating agent, water temperature, and time of exposure significantly (p <0.05) affected florfenicol leaching, while water pH did not interfere with the leaching. Coating with vegetable oil was the most efficient method to reduce florfenicol leaching, while coating with carboxymethylcellulose presented the highest leaching (approximately 60% after 15 min at 28°C). Thus, the coating agent has a significant effect on the florfenicol leaching rate and, consequently, on the necessary dose of the drug to be administered. Moreover, it is worth mentioning that higher florfenicol leaching will pose a greater risk to environmental health, specifically in terms of the development of bacteria resistant to florfenicol. Additional studies are needed with other polymers and veterinary drugs used in medicated feed for fish farming. MenosFlorfenicol is one of the most-used antimicrobial agents in global fish farming. Nevertheless, in most countries, its use is not conducted in accordance with good practices. The aim of this work was to evaluate the leaching of florfenicol from coated fish feed into the water. Analytical methods were developed and validated for the quantitation of florfenicol in medicated feed and water by UHPLC-MS/MS. Florfenicol residues in the water were quantified after 5- and 15-min exposures of the medicated feed in the water at 22 and 28°C and at pH 4.5 and 8.0. The influence of pellet size and three coating agents (vegetable oil, carboxymethylcellulose, and low-methoxylated pectin) on the leaching of the drug was also assessed. Pellet size, coating agent, water temperature, and time of exposure significantly (p <0.05) affected florfenicol leaching, while water pH did not interfere with the leaching. Coating with vegetable oil was the most efficient method to reduce florfenicol leaching, while coating with carboxymethylcellulose presented the highest leaching (approximately 60% after 15 min at 28°C). Thus, the coating agent has a significant effect on the florfenicol leaching rate and, consequently, on the necessary dose of the drug to be administered. Moreover, it is worth mentioning that higher florfenicol leaching will pose a greater risk to environmental health, specifically in terms of the development of bacteria resistant to florfenicol. Additional studies are needed with other p... Mostrar Tudo |
Thesagro: |
Antibiótico; Florfenicol; Lixiviação; Piscicultura. |
Thesaurus Nal: |
Antibiotics; Carboxymethylcellulose; Fish feeds; Leaching; Pectins. |
Categoria do assunto: |
P Recursos Naturais, Ciências Ambientais e da Terra |
Marc: |
LEADER 02473naa a2200313 a 4500 001 2098693 005 2018-11-01 008 2018 bl uuuu u00u1 u #d 022 $a0269-7491 024 7 $ahttps://doi.org/10.1016/j.envpol.2018.08.017$2DOI 100 1 $aBARRETO, F. M. 245 $aEvaluation of the leaching of florfenicol from coated medicated fish feed into water.$h[electronic resource] 260 $c2018 520 $aFlorfenicol is one of the most-used antimicrobial agents in global fish farming. Nevertheless, in most countries, its use is not conducted in accordance with good practices. The aim of this work was to evaluate the leaching of florfenicol from coated fish feed into the water. Analytical methods were developed and validated for the quantitation of florfenicol in medicated feed and water by UHPLC-MS/MS. Florfenicol residues in the water were quantified after 5- and 15-min exposures of the medicated feed in the water at 22 and 28°C and at pH 4.5 and 8.0. The influence of pellet size and three coating agents (vegetable oil, carboxymethylcellulose, and low-methoxylated pectin) on the leaching of the drug was also assessed. Pellet size, coating agent, water temperature, and time of exposure significantly (p <0.05) affected florfenicol leaching, while water pH did not interfere with the leaching. Coating with vegetable oil was the most efficient method to reduce florfenicol leaching, while coating with carboxymethylcellulose presented the highest leaching (approximately 60% after 15 min at 28°C). Thus, the coating agent has a significant effect on the florfenicol leaching rate and, consequently, on the necessary dose of the drug to be administered. Moreover, it is worth mentioning that higher florfenicol leaching will pose a greater risk to environmental health, specifically in terms of the development of bacteria resistant to florfenicol. Additional studies are needed with other polymers and veterinary drugs used in medicated feed for fish farming. 650 $aAntibiotics 650 $aCarboxymethylcellulose 650 $aFish feeds 650 $aLeaching 650 $aPectins 650 $aAntibiótico 650 $aFlorfenicol 650 $aLixiviação 650 $aPiscicultura 700 1 $aSILVA, M. R. da 700 1 $aBRAGA, P. A. C. 700 1 $aBRAGOTTO, A. P. A. 700 1 $aHISANO, H. 700 1 $aREYES, F. G. R. 773 $tEnvironmental Pollution$gv. 242, Part B, p. 1245-1252, 2018.
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Registro original: |
Embrapa Meio Ambiente (CNPMA) |
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| Acesso ao texto completo restrito à biblioteca da Embrapa Agrobiologia. Para informações adicionais entre em contato com cnpab.biblioteca@embrapa.br. |
Registro Completo
Biblioteca(s): |
Embrapa Agrobiologia. |
Data corrente: |
02/02/2004 |
Data da última atualização: |
02/02/2004 |
Autoria: |
MACHADO, R. L.; MOREIRA, J. F.; FARIA, S. M. de. |
Título: |
Seleção de estirpes de rizóbio para leguminosas com potencial de uso na recuperação de áreas degradadas. |
Ano de publicação: |
2003 |
Fonte/Imprenta: |
In; CONGRESSO BRASILEIRO DE CIÊNCIA DO SOLO, 29., 2003, Ribeirão Preto. Resumos... Botucatu: SBCS, 2003. |
Páginas: |
4 p. |
Idioma: |
Português |
Palavras-Chave: |
Degradação do solo; Soil deterioration; Soil reclamation. |
Thesagro: |
Deterioração do Solo; Recuperação do Solo. |
Thesaurus NAL: |
soil degradation. |
Categoria do assunto: |
-- |
Marc: |
LEADER 00723naa a2200217 a 4500 001 1623648 005 2004-02-02 008 2003 bl --- 0-- u #d 100 1 $aMACHADO, R. L. 245 $aSeleção de estirpes de rizóbio para leguminosas com potencial de uso na recuperação de áreas degradadas. 260 $c2003 300 $a4 p. 650 $asoil degradation 650 $aDeterioração do Solo 650 $aRecuperação do Solo 653 $aDegradação do solo 653 $aSoil deterioration 653 $aSoil reclamation 700 1 $aMOREIRA, J. F. 700 1 $aFARIA, S. M. de 773 $tIn; CONGRESSO BRASILEIRO DE CIÊNCIA DO SOLO, 29., 2003, Ribeirão Preto. Resumos... Botucatu: SBCS, 2003.
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